The Amino-Terminal Region of Vpr from Human Immunodeficiency Virus Type 1 Forms Ion Channels and Kills Neurons

We have previously reported that the accessory protein Vpr from human immunodeficiency virus type 1 forms cation-selective ion channels in planar lipid bilayers and is able to depolarize intact cultured neurons by causing an inward sodium current, resulting in cell death. In this study, we used site...

Full description

Saved in:
Bibliographic Details
Main Authors: Piller, S. C., Ewart, G. D., Jans, D. A., Gage, P. W., Cox, G. B.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC104202/
https://ncbi.nlm.nih.gov/pubmed/10196319
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items