CpG-Containing Oligonucleotides Are Efficient Adjuvants for Induction of Protective Antiviral Immune Responses with T-Cell Peptide Vaccines

Synthetic nonmethylated oligonucleotides containing CpG dinucleotides (CpG-ODNs) have been shown to exhibit immunostimulatory activity. CpG-ODNs have the capacity to directly activate B cells, macrophages, and dendritic cells, and we show here that this is reflected by cell surface binding of oligon...

Full description

Saved in:
Bibliographic Details
Main Authors: Oxenius, Annette, Martinic, Marianne M. A., Hengartner, Hans, Klenerman, Paul
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC104191/
https://ncbi.nlm.nih.gov/pubmed/10196308
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items