Iκκ Mediates NF-κB Activation in Human Immunodeficiency Virus-Infected Cells

Human monocytes and macrophages are persistent reservoirs of human immunodeficiency virus (HIV) type-1. Persistent HIV infection of these cells results in increased levels of NF-κB in the nucleus secondary to increased IκBα, IκBβ, and IκBɛ degradation, a mechanism postulated to regulate viral persis...

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Bibliographic Details
Main Authors: Asin, Susana, Taylor, Julie A., Trushin, Sergey, Bren, Gary, Paya, Carlos V.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC104167/
https://ncbi.nlm.nih.gov/pubmed/10196284
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