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Iκκ Mediates NF-κB Activation in Human Immunodeficiency Virus-Infected Cells

Human monocytes and macrophages are persistent reservoirs of human immunodeficiency virus (HIV) type-1. Persistent HIV infection of these cells results in increased levels of NF-κB in the nucleus secondary to increased IκBα, IκBβ, and IκBɛ degradation, a mechanism postulated to regulate viral persis...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Asin, Susana, Taylor, Julie A., Trushin, Sergey, Bren, Gary, Paya, Carlos V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1999
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104167/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10196284/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.5.3893-3903.1999
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