Transduction of Human Progenitor Hematopoietic Stem Cells by Human Immunodeficiency Virus Type 1-Based Vectors Is Cell Cycle Dependent

Human immunodeficiency virus (HIV) type 1 vectors are highly efficient in their ability to transduce human progenitor hematopoietic stem cells (PHSC). Although mitosis was not required for transduction of these cells, transduction rates were much greater once cells had been cultured in the presence...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Sutton, Richard E., Reitsma, Michael J., Uchida, Nobuko, Brown, Patrick O.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Gene Therapy
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104140/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10196257/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.5.3649-3660.1999
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