Transduction of Human Progenitor Hematopoietic Stem Cells by Human Immunodeficiency Virus Type 1-Based Vectors Is Cell Cycle Dependent

Human immunodeficiency virus (HIV) type 1 vectors are highly efficient in their ability to transduce human progenitor hematopoietic stem cells (PHSC). Although mitosis was not required for transduction of these cells, transduction rates were much greater once cells had been cultured in the presence...

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Détails bibliographiques

Publié dans:	J Virol
Auteurs principaux:	Sutton, Richard E., Reitsma, Michael J., Uchida, Nobuko, Brown, Patrick O.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1999
Sujets:	Gene Therapy
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104140/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10196257/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.5.3649-3660.1999
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