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Highly Potent RANTES Analogues either Prevent CCR5-Using Human Immunodeficiency Virus Type 1 Infection In Vivo or Rapidly Select for CXCR4-Using Variants

The natural ligands for the CCR5 chemokine receptor, macrophage inflammatory protein 1α (MIP-1α), MIP-1β, and RANTES (regulated on T-cell activation, normal T-cell expressed and secreted), are known to inhibit human immunodeficiency virus (HIV) entry, and N-terminally modified RANTES analogues are m...

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Published in:J Virol
Main Authors: Mosier, Donald E., Picchio, Gastón R., Gulizia, Richard J., Sabbe, Rebecca, Poignard, Pascal, Picard, Laurent, Offord, Robin E., Thompson, Darren A., Wilken, Jill
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1999
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104126/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10196243/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.5.3544-3550.1999
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