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Effectiveness of Polyene Antibiotics in Treatment of Transmissible Spongiform Encephalopathy in Transgenic Mice Expressing Syrian Hamster PrP Only in Neurons

To date very few drugs have favorably influenced the course of transmissible spongiform encephalopathies. In previous studies, the polyene antibiotics amphotericin B (AmB) and MS-8209 prolonged the incubation time in Syrian hamsters of the 263K strain of scrapie, but AmB had no effect against other...

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Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Demaimay, Remi, Race, Richard, Chesebro, Bruce
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1999
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104121/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10074211/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.4.3511-3513.1999
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