The Ski7 Antiviral Protein Is an EF1-α Homolog That Blocks Expression of Non-Poly(A) mRNA in Saccharomyces cerevisiae

We mapped and cloned SKI7, a gene that negatively controls the copy number of L-A and M double-stranded RNA viruses in Saccharomyces cerevisiae. We found that it encodes a nonessential 747-residue protein with similarities to two translation factors, Hbs1p and EF1-α. The ski7 mutant was hypersensiti...

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Autori principali: Benard, Lionel, Carroll, Kathleen, Valle, Rosaura C. P., Masison, Daniel C., Wickner, Reed B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1999
Soggetti:
Virus-Cell Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC104047/
https://ncbi.nlm.nih.gov/pubmed/10074137
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