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The Ski7 Antiviral Protein Is an EF1-α Homolog That Blocks Expression of Non-Poly(A) mRNA in Saccharomyces cerevisiae

We mapped and cloned SKI7, a gene that negatively controls the copy number of L-A and M double-stranded RNA viruses in Saccharomyces cerevisiae. We found that it encodes a nonessential 747-residue protein with similarities to two translation factors, Hbs1p and EF1-α. The ski7 mutant was hypersensiti...

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Vydáno v:J Virol
Hlavní autoři: Benard, Lionel, Carroll, Kathleen, Valle, Rosaura C. P., Masison, Daniel C., Wickner, Reed B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1999
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On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104047/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10074137/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.4.2893-2900.1999
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