Woodchuck Hepatitis Virus Posttranscriptional Regulatory Element Enhances Expression of Transgenes Delivered by Retroviral Vectors

The expression of genes delivered by retroviral vectors is often inefficient, a potential obstacle for their widespread use in human gene therapy. Here, we explored the possibility that the posttranscriptional regulatory element of woodchuck hepatitis virus (WPRE) might help resolve this problem. In...

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Dettagli Bibliografici

Pubblicato in:	J Virol
Autori principali:	Zufferey, Romain, Donello, John E., Trono, Didier, Hope, Thomas J.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1999
Soggetti:	Gene Therapy
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104046/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10074136/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.4.2886-2892.1999
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