Drastic Fitness Loss in Human Immunodeficiency Virus Type 1 upon Serial Bottleneck Events

Muller’s ratchet predicts fitness losses in small populations of asexual organisms because of the irreversible accumulation of deleterious mutations and genetic drift. This effect should be enhanced if population bottlenecks intervene and fixation of mutations is not compensated by recombination. To...

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Dades bibliogràfiques

Publicat a:	J Virol
Autors principals:	Yuste, Eloisa, Sánchez-Palomino, Sonsoles, Casado, Concha, Domingo, Esteban, López-Galíndez, Cecilio
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1999
Matèries:	Recombination and Evolution
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104031/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10074121/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.4.2745-2751.1999
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