Exponential Fitness Gains of RNA Virus Populations Are Limited by Bottleneck Effects

Fitness is a parameter that quantitatively measures adaptation of a virus to a given environment. We have previously reported exponential fitness gains of large populations of vesicular stomatitis virus replicating in a constant environment (I. S. Novella et al., Proc. Natl. Acad. Sci. USA 92:5841–5...

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Bibliographic Details
Main Authors: Novella, Isabel S., Quer, Josep, Domingo, Esteban, Holland, John J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Recombination and Evolution
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC103997/
https://ncbi.nlm.nih.gov/pubmed/9882378
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