Endoproteolytic Processing of the Ebola Virus Envelope Glycoprotein: Cleavage Is Not Required for Function

Proteolytic processing is required for the activation of numerous viral glycoproteins. Here we show that the envelope glycoprotein from the Zaire strain of Ebola virus (Ebo-GP) is proteolytically processed into two subunits, GP(1) and GP(2), that are likely covalently associated through a disulfide...

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Pubblicato in:	J Virol
Autori principali:	Wool-Lewis, Rouven J., Bates, Paul
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1999
Soggetti:	Replication
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103966/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9882347/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.2.1419-1426.1999
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