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Endoproteolytic Processing of the Ebola Virus Envelope Glycoprotein: Cleavage Is Not Required for Function

Proteolytic processing is required for the activation of numerous viral glycoproteins. Here we show that the envelope glycoprotein from the Zaire strain of Ebola virus (Ebo-GP) is proteolytically processed into two subunits, GP(1) and GP(2), that are likely covalently associated through a disulfide...

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Publicado no:J Virol
Principais autores: Wool-Lewis, Rouven J., Bates, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1999
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103966/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9882347/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.2.1419-1426.1999
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