Human T-Cell Leukemia Virus Type 1 Tax Protein Abrogates Interleukin-2 Dependence in a Mouse T-Cell Line

Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia. Tax, the viral protein, is thought to be crucial in the development of the disease, since it transforms healthy T cells in vitro and induces tumors in transgenic animals. We examined the effect of Tax activi...

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Main Authors: Iwanaga, Youichi, Tsukahara, Tomonori, Ohashi, Takashi, Tanaka, Yuetsu, Arai, Masaaki, Nakamura, Masataka, Ohtani, Kiyoshi, Koya, Yoshihiro, Kannagi, Mari, Yamamoto, Naoki, Fujii, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC103950/
https://ncbi.nlm.nih.gov/pubmed/9882331
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