Induction of Bcl-x(L) Expression by Human T-Cell Leukemia Virus Type 1 Tax through NF-κB in Apoptosis-Resistant T-Cell Transfectants with Tax

Human T-cell leukemia virus type 1 (HTLV-1) Tax is thought to play a pivotal role in immortalization of T cells. We have recently shown that the expression of Tax protected the mouse T-cell line CTLL-2 against apoptosis induced by interleukin-2 (IL-2) deprivation and converted its growth from being...

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Detalhes bibliográficos
Main Authors: Tsukahara, Tomonori, Kannagi, Mari, Ohashi, Takashi, Kato, Hirotomo, Arai, Masaaki, Nunez, Gabriel, Iwanaga, Youichi, Yamamoto, Naoki, Ohtani, Kiyoshi, Nakamura, Masataka, Fujii, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1999
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC112812/
https://ncbi.nlm.nih.gov/pubmed/10482545
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