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Insertion of Foreign DNA into an Established Mammalian Genome Can Alter the Methylation of Cellular DNA Sequences

The insertion of adenovirus type 12 (Ad12) DNA into the hamster genome and the transformation of these cells by Ad12 can lead to marked alterations in the levels of DNA methylation in several cellular genes and DNA segments. Since such alterations in DNA methylation patterns are likely to affect the...

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Auteurs principaux: Remus, Ralph, Kämmer, Christina, Heller, Hilde, Schmitz, Birgit, Schell, Gudrun, Doerfler, Walter
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC103921/
https://ncbi.nlm.nih.gov/pubmed/9882302
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