RNase L Inhibitor Is Induced during Human Immunodeficiency Virus Type 1 Infection and Down Regulates the 2-5A/RNase L Pathway in Human T Cells

The interferon-regulated 2-5A/RNase L pathway plays a major role in the antiviral and antiproliferative activities of these cytokines. Several viruses, however, have evolved strategies to escape the antiviral activity of the 2-5A/RNase L pathway. In this context, we have cloned a cDNA coding for the...

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Bibliographische Detailangaben
Hauptverfasser: Martinand, Camille, Montavon, Céline, Salehzada, Tamim, Silhol, Michelle, Lebleu, Bernard, Bisbal, Catherine
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1999
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC103833/
https://ncbi.nlm.nih.gov/pubmed/9847332
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