Overexpression of a Dominant-Negative Allele of SEC4 Inhibits Growth and Protein Secretion in Candida albicans

Candida albicans SEC4 was cloned by complementing the Saccharomyces cerevisiae sec4-8 mutation, and its deduced protein product (Sec4p) was 63% identical to S. cerevisiae Sec4p. One chromosomal SEC4 allele in C. albicans CAI4 was readily disrupted by homologous gene targeting, but efforts to disrupt...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Mao, Yuxin, Kalb, Vernon F., Wong, Brian
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Eukaryotic Cells
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103685/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10572126/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.181.23.7235-7242.1999
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