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Analysis of Mutations in the Pore-Forming Region Essential for Insecticidal Activity of a Bacillus thuringiensis δ-Endotoxin

The Bacillus thuringiensis insecticidal δ-endotoxins have a three-domain structure, with the seven amphipathic helices which comprise domain I being essential for toxicity. To better define the function of these helices in membrane insertion and toxicity, either site-directed or random mutagenesis o...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Bacteriol
Hauptverfasser: Manoj Kumar, A. S., Aronson, A. I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1999
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103639/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10498724/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.181.19.6103-6107.1999
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