Analysis of Mutations in the Pore-Forming Region Essential for Insecticidal Activity of a Bacillus thuringiensis δ-Endotoxin

The Bacillus thuringiensis insecticidal δ-endotoxins have a three-domain structure, with the seven amphipathic helices which comprise domain I being essential for toxicity. To better define the function of these helices in membrane insertion and toxicity, either site-directed or random mutagenesis o...

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Pubblicato in:	J Bacteriol
Autori principali:	Manoj Kumar, A. S., Aronson, A. I.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1999
Soggetti:	Genetics and Molecular Biology
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103639/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10498724/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.181.19.6103-6107.1999
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