A Mutant HemA Protein with Positive Charge Close to the N Terminus Is Stabilized against Heme-Regulated Proteolysis in Salmonella typhimurium

The HemA enzyme (glutamyl-tRNA reductase) catalyzes the first committed step in heme biosynthesis in the enteric bacteria. HemA is mainly regulated by conditional protein stability; it is stable and, consequently, more abundant in heme-limited cells but unstable and less abundant in normally growing...

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Pubblicato in:	J Bacteriol
Autori principali:	Wang, Liying, Wilson, Sandra, Elliott, Thomas
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1999
Soggetti:	Genetics and Molecular Biology
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103631/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10498716/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.181.19.6033-6041.1999
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