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A Mutant HemA Protein with Positive Charge Close to the N Terminus Is Stabilized against Heme-Regulated Proteolysis in Salmonella typhimurium

The HemA enzyme (glutamyl-tRNA reductase) catalyzes the first committed step in heme biosynthesis in the enteric bacteria. HemA is mainly regulated by conditional protein stability; it is stable and, consequently, more abundant in heme-limited cells but unstable and less abundant in normally growing...

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Bibliografiska uppgifter
Huvudupphovsmän: Wang, Liying, Wilson, Sandra, Elliott, Thomas
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 1999
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC103631/
https://ncbi.nlm.nih.gov/pubmed/10498716
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