The Streptomyces peucetius dpsC Gene Determines the Choice of Starter Unit in Biosynthesis of the Daunorubicin Polyketide

The starter unit used in the biosynthesis of daunorubicin is propionyl coenzyme A (CoA) rather than acetyl-CoA, which is used in the production of most of the bacterial aromatic polyketides studied to date. In the daunorubicin biosynthesis gene cluster of Streptomyces peucetius, directly downstream...

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Bibliographic Details

Published in:	J Bacteriol
Main Authors:	Bao, Wuli, Sheldon, Paul J., Wendt-Pienkowski, Evelyn, Hutchinson, C. Richard
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1999
Subjects:	Genetics and Molecular Biology
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103607/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10419974/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.181.15.4690-4695.1999
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