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Amino Acid Residues Involved in the Functional Integrity of Escherichia coli Methionine Aminopeptidase

Amino acid residues in the metal-binding and putative substrate-binding sites of Escherichia coli methionine aminopeptidase (MAP) were mutated, and their effects on the function of the enzyme were investigated. Substitution of any amino acid residue at the metal-binding site resulted in complete los...

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Main Authors: Chiu, Chen-Hsiang, Lee, Chao-Zong, Lin, Kung-Shih, Tam, Ming F., Lin, Lih-Yuan
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC103606/
https://ncbi.nlm.nih.gov/pubmed/10419973
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