Doxorubicin Overproduction in Streptomyces peucetius: Cloning and Characterization of the dnrU Ketoreductase and dnrV Genes and the doxA Cytochrome P-450 Hydroxylase Gene

Doxorubicin-overproducing strains of Streptomyces peucetius ATCC 29050 can be obtained through manipulation of the genes in the region of the doxorubicin (DXR) gene cluster that contains dpsH, the dpsG polyketide synthase gene, the putative dnrU ketoreductase gene, dnrV, and the doxA cytochrome P-45...

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Detaylı Bibliyografya

Yayımlandı:	J Bacteriol
Asıl Yazarlar:	Lomovskaya, Natalie, Otten, Sharee L., Doi-Katayama, Yukiko, Fonstein, Leonid, Liu, Xiao-Chun, Takatsu, Toshio, Inventi-Solari, Augusto, Filippini, Silvia, Torti, Francesca, Colombo, Anna Luisa, Hutchinson, C. Richard
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	American Society for Microbiology (ASM) 1999
Konular:	Genetics and Molecular Biology
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103563/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9864344/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.181.1.305-318.1999
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