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Structural basis for uracil DNA glycosylase interaction with uracil: NMR study

Two dimensional (2D) NMR and molecular dynamics simulations have been used to determine the three dimensional (3D) structure of a hairpin DNA, d-CTA-GAGGATCC-TUTT-GGATCCT (22mer; abbreviated as U2-hairpin), which has uracil at the second position from the 5′ end of the tetraloop. The (1)H resonances...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ghosh, Mahua, Vinay Kumar, N., Varshney, Umesh, Chary, K. V. R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC103296/
https://ncbi.nlm.nih.gov/pubmed/10756190
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