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Structural basis for uracil DNA glycosylase interaction with uracil: NMR study

Two dimensional (2D) NMR and molecular dynamics simulations have been used to determine the three dimensional (3D) structure of a hairpin DNA, d-CTA-GAGGATCC-TUTT-GGATCCT (22mer; abbreviated as U2-hairpin), which has uracil at the second position from the 5′ end of the tetraloop. The (1)H resonances...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Ghosh, Mahua, Vinay Kumar, N., Varshney, Umesh, Chary, K. V. R.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2000
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103296/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10756190/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.9.1906
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