2-Hydroxy-dATP is incorporated opposite G by Escherichia coli DNA polymerase III resulting in high mutagenicity

Four kinds of oxidatively damaged DNA precursors, 8-hydroxydeoxyguanosine 5′-triphosphate (8-OH-dGTP), 2-hydroxydeoxyadenosine 5′-triphosphate (2-OH-dATP), 5-hydroxydeoxycytidine 5′-triphosphate (5-OH-dCTP) and 5-formyldeoxyuridine 5′-triphosphate (5-CHO-dUTP), were employed in in vitro gap-filling...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Kamiya, Hiroyuki, Kasai, Hiroshi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 2000
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102799/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10710431/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.7.1640
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