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Human RecQ5β, a large isomer of RecQ5 DNA helicase, localizes in the nucleoplasm and interacts with topoisomerases 3α and 3β

The RecQ helicase superfamily has been implicated in DNA repair and recombination. At least five human RecQ-related genes exist: RecQ1, BLM, WRN, RecQ4 and RecQ5. Mutations in BLM, WRN and RecQ4 are associated with Bloom, Werner and Rothmund-Thomson syndromes, respectively, involving a predispositio...

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Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Shimamoto, Akira, Nishikawa, Kaori, Kitao, Saori, Furuichi, Yasuhiro
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2000
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102787/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10710432/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.7.1647
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