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In vitro DNA synthesis opposite oxazolone and repair of this DNA damage using modified oligonucleotides

Emphasis was placed in this work on the assessment of biological features of 2,2,4-triaminooxazolone, a major one-electron and (·)OH-mediated oxidation product of guanine. For this purpose, two oligonucleotides that contain a unique oxazolone residue were synthesized. Herein we report the mutagenic...

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Hlavní autoři: Duarte, Victor, Gasparutto, Didier, Jaquinod, Michel, Cadet, Jean
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC102781/
https://ncbi.nlm.nih.gov/pubmed/10710422
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