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PCR-generated padlock probes detect single nucleotide variation in genomic DNA

Circularizing oligonucleotide probes, so-called padlock probes, have properties that should prove valuable in a wide range of genetic investigations, including in situ analyses, genotyping and measurement of gene expression. However, padlock probes can be difficult to obtain by standard oligonucleot...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Antson, D.-O., Isaksson, A., Landegren, U., Nilsson, M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC102743/
https://ncbi.nlm.nih.gov/pubmed/10871381
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