Characterization of the human and mouse WRN 3′→5′ exonuclease
Werner’s syndrome (WS) is an autosomal recessive disorder in humans characterized by the premature development of a partial array of age-associated pathologies. WRN, the gene defective in WS, encodes a 1432 amino acid protein (hWRN) with intrinsic 3′→5′ DNA helicase activity. We recently showed that...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2000
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102739/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10871373/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.12.2396 |
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