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Characterization of the human and mouse WRN 3′→5′ exonuclease

Werner’s syndrome (WS) is an autosomal recessive disorder in humans characterized by the premature development of a partial array of age-associated pathologies. WRN, the gene defective in WS, encodes a 1432 amino acid protein (hWRN) with intrinsic 3′→5′ DNA helicase activity. We recently showed that...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Huang, Shurong, Beresten, Sergey, Li, Baomin, Oshima, Junko, Ellis, Nathan A., Campisi, Judith
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102739/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10871373/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.12.2396
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