Resolution of a Holliday junction by vaccinia topoisomerase requires a spacer DNA segment 3′ of the CCCTT↓ cleavage sites
Vaccinia virus DNA topoisomerase catalyzes resolution of synthetic Holliday junctions in vitro. The mechanism entails concerted transesterifications at two recognition sites, 5′-CCCTT↓, that are opposed within a partially mobile four-way junction. Efficient resolution occurs on a junction with a 10...
Uloženo v:
| Vydáno v: | Nucleic Acids Res |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2000
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102645/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10908320/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.14.2658 |
| Tagy: |
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
|
