An ‘environment to nucleus’ signaling system operates in B lymphocytes: redox status modulates BSAP/Pax-5 activation through Ref-1 nuclear translocation

The Ref-1 (also called APE or HAP1) protein is a bifunctional enzyme impacting on a wide variety of important cellular functions. It acts as a major member of the DNA base excision repair pathway. Moreover, Ref-1 stimulates the DNA-binding activity of several transcription factors (TFs) through the...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Tell, Gianluca, Zecca, Alessandro, Pellizzari, Lucia, Spessotto, Paola, Colombatti, Alfonso, Kelley, Mark R., Damante, Giuseppe, Pucillo, Carlo
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 2000
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102597/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10666449/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.5.1099
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