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Activation of APE/Ref-1 redox activity is mediated by reactive oxygen species and PKC phosphorylation

Reactive oxygen species (ROS) arise through normal cellular aerobic respiration, and, in combination with external sources such as ionizing radiation, cigarette tar and smoke, and particulate matter generated by combustion, can have a profound negative effect on cellular macromolecules such as DNA t...

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Main Authors: Hsieh, Marlene M., Hegde, Vijay, Kelley, Mark R., Deutsch, Walter A.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC55809/
https://ncbi.nlm.nih.gov/pubmed/11452037
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