Influence of correct secondary and tertiary RNA folding on the binding of cellular factors to the HCV IRES

Structural integrity of the hepatitus C virus (HCV) 5′ UTR region that includes the internal ribosome entry site (IRES) element is known to be essential for efficient protein synthesis. The functional explanation for this observation has been provided by the recent evidence that binding of several c...

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הוצא לאור ב:	Nucleic Acids Res
Principais autores:	Odreman-Macchioli, F. E., Tisminetzky, S. G., Zotti, M., Baralle, F. E., Buratti, E.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Oxford University Press 2000
נושאים:	Article
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102586/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10648778/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.4.875
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