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Avoidance of tolerance and lack of rebound with intermittent dose titrated transdermal glyceryl trinitrate. The Transdermal Nitrate Investigators.

OBJECTIVES--To investigate the efficacy of transdermal glyceryl trinitrate given continuously and with a nocturnal nitrate free period. DESIGN--Double blind placebo controlled study with two parallel limbs. SETTING--Multicentre trial. PATIENTS--52 patients randomised to receive either continuous tre...

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Опубликовано в: :Br Heart J
Главные авторы: Fox, K M, Dargie, H J, Deanfield, J, Maseri, A
Формат: Artigo
Язык:Inglês
Опубликовано: BMJ Publishing Group 1991
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC1024608/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1909152/
https://ncbi.nlm.nih.govhttps://doi.org/10.1136/hrt.66.2.151
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