Avoidance of tolerance and lack of rebound with intermittent dose titrated transdermal glyceryl trinitrate. The Transdermal Nitrate Investigators.

OBJECTIVES--To investigate the efficacy of transdermal glyceryl trinitrate given continuously and with a nocturnal nitrate free period. DESIGN--Double blind placebo controlled study with two parallel limbs. SETTING--Multicentre trial. PATIENTS--52 patients randomised to receive either continuous tre...

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Main Authors: Fox, K M, Dargie, H J, Deanfield, J, Maseri, A
格式: Artigo
語言:Inglês
出版: 1991
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1024608/
https://ncbi.nlm.nih.gov/pubmed/1909152
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