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Regulation of Fab1 Phosphatidylinositol 3-Phosphate 5-Kinase Pathway by Vac7 Protein and Fig4, a Polyphosphoinositide Phosphatase Family Member

The Saccharomyces cerevisiae FAB1 gene encodes the sole phosphatidylinositol 3-phosphate [PtdIns(3)P] 5-kinase responsible for synthesis of the polyphosphoinositide PtdIns(3,5)P(2). VAC7 encodes a 128-kDa transmembrane protein that localizes to vacuolar membranes. Both vac7 and fab1 null mutants hav...

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Detalhes bibliográficos
Main Authors: Gary, Jonathan D., Sato, Trey K., Stefan, Christopher J., Bonangelino, Cecilia J., Weisman, Lois S., Emr, Scott D.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC102265/
https://ncbi.nlm.nih.gov/pubmed/11950935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.01-10-0498
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