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Magnitude of the CREB-Dependent Transcriptional Response Is Determined by the Strength of the Interaction between the Kinase-Inducible Domain of CREB and the KIX Domain of CREB-Binding Protein

The activity of the transcription factor CREB is regulated by extracellular stimuli that result in its phosphorylation at a critical serine residue, Ser133. Phosphorylation of Ser133 is believed to promote CREB-dependent transcription by allowing CREB to interact with the transcriptional coactivator...

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Hlavní autoři: Shaywitz, Adam J., Dove, Simon L., Kornhauser, Jon M., Hochschild, Ann, Greenberg, Michael E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC102197/
https://ncbi.nlm.nih.gov/pubmed/11094091
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