Induced Expression of Rnd3 Is Associated with Transformation of Polarized Epithelial Cells by the Raf–MEK–Extracellular Signal-Regulated Kinase Pathway

Madin-Darby canine kidney (MDCK) epithelial cells transformed by oncogenic Ras and Raf exhibit cell multilayering and alterations in the actin cytoskeleton. The changes in the actin cytoskeleton comprise a loss of actin stress fibers and enhanced cortical actin. Using MDCK cells expressing a conditi...

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Detalhes bibliográficos
Main Authors: Hansen, Steen H., Zegers, Mirjam M. P., Woodrow, Melissa, Rodriguez-Viciana, Pablo, Chardin, Pierre, Mostov, Keith E., McMahon, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC102193/
https://ncbi.nlm.nih.gov/pubmed/11094087
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