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Hepatocyte Growth Factor Switches Orientation of Polarity and Mode of Movement during Morphogenesis of Multicellular Epithelial Structures

Epithelial cells form monolayers of polarized cells with apical and basolateral surfaces. Madin-Darby canine kidney epithelial cells transiently lose their apico-basolateral polarity and become motile by treatment with hepatocyte growth factor (HGF), which causes the monolayer to remodel into tubule...

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Autori principali: Yu, Wei, O'Brien, Lucy E., Wang, Fei, Bourne, Henry, Mostov, Keith E., Zegers, Mirjam M.P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC150005/
https://ncbi.nlm.nih.gov/pubmed/12589067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-06-0350
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