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Cyclic AMP Promotes Neuronal Survival by Phosphorylation of Glycogen Synthase Kinase 3β

Agents that elevate intracellular cyclic AMP (cAMP) levels promote neuronal survival in a manner independent of neurotrophic factors. Inhibitors of phosphatidylinositol 3 kinase and dominant-inactive mutants of the protein kinase Akt do not block the survival effects of cAMP, suggesting that another...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Mingtao, Wang, Xiaomin, Meintzer, Mary Kay, Laessig, Tracey, Birnbaum, Morris J., Heidenreich, Kim A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC102192/
https://ncbi.nlm.nih.gov/pubmed/11094086
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