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Ras-Dependent Regulation of c-Jun Phosphorylation Is Mediated by the Ral Guanine Nucleotide Exchange Factor-Ral Pathway

The transcription factor c-Jun is critically involved in the regulation of proliferation and differentiation as well as cellular transformation induced by oncogenic Ras. The signal transduction pathways that couple Ras activation to c-Jun phosphorylation are still partially elusive. Here we show tha...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: de Ruiter, Nancy D., Wolthuis, Rob M. F., van Dam, Hans, Burgering, Boudewijn M. T., Bos, Johannes L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC102154/
https://ncbi.nlm.nih.gov/pubmed/11046144
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