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The Absence of Msh2 Alters Abelson Virus Pre-B-Cell Transformation by Influencing p53 Mutation

Defects in DNA mismatch repair predispose cells to the development of several types of malignant disease. The absence of Msh2 or Mlh1, two key molecules that mediate mismatch repair in eukaryotic cells, increases the frequency of mutation and also alters the response of some cells to apoptosis and c...

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Autors principals: Jenab-Wolcott, Jenia, Rodriguez-Correa, Daniel, Reitmair, Armin H., Mak, Tak, Rosenberg, Naomi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC102144/
https://ncbi.nlm.nih.gov/pubmed/11046134
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