Distinct Trafficking Pathways Mediate Nef-Induced and Clathrin-Dependent Major Histocompatibility Complex Class I Down-Regulation

The human immunodeficiency virus type 1 Nef protein alters the post-Golgi stages of major histocompatibility complex class I (MHC-I) biogenesis. Presumed mechanisms involve the disclosure of a cryptic tyrosine-based sorting signal (YSQA) located in the cytoplasmic tail of HLA-A and -B heavy chains....

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Pubblicato in:	J Virol
Autori principali:	Le Gall, Sylvie, Buseyne, Florence, Trocha, Alicja, Walker, Bruce D., Heard, Jean-Michel, Schwartz, Olivier
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Virus-Cell Interactions
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102125/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10982373/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.19.9256-9266.2000
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