Effect of an inhaled neutral endopeptidase inhibitor, phosphoramidon, on baseline airway calibre and bronchial responsiveness to bradykinin in asthma.

BACKGROUND--Bradykinin is a potent vasoactive peptide which has been proposed as an important inflammatory mediator in asthma since it provokes potent bronchoconstriction in asthmatic subjects. Little is known at present about the potential role of lung peptidases in modulating bradykinin-induced ai...

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Bibliografiske detaljer
Main Authors: Crimi, N., Polosa, R., Pulvirenti, G., Magrì, S., Santonocito, G., Prosperini, G., Mastruzzo, C., Mistretta, A.
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1021219/
https://ncbi.nlm.nih.gov/pubmed/7597662
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