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Low-Level Secretion of Human Hepatitis B Virus Virions Caused by Two Independent, Naturally Occurring Mutations (P5T and L60V) in the Capsid Protein

The functional significance of naturally occurring variants of human hepatitis B virus (HBV) remains largely unknown. Previously, we reported an immature secretion phenotype caused by a highly frequent mutation at amino acid 97 of the HBV core (capsid) protein (HBcAg). This phenotype is characterize...

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Detalhes bibliográficos
Main Authors: Le Pogam, Sophie, Yuan, Thomas Ta-Tung, Sahu, Gautam Kumar, Chatterjee, Soma, Shih, Chiaho
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC102108/
https://ncbi.nlm.nih.gov/pubmed/10982356
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