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Low-Level Secretion of Human Hepatitis B Virus Virions Caused by Two Independent, Naturally Occurring Mutations (P5T and L60V) in the Capsid Protein

The functional significance of naturally occurring variants of human hepatitis B virus (HBV) remains largely unknown. Previously, we reported an immature secretion phenotype caused by a highly frequent mutation at amino acid 97 of the HBV core (capsid) protein (HBcAg). This phenotype is characterize...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Le Pogam, Sophie, Yuan, Thomas Ta-Tung, Sahu, Gautam Kumar, Chatterjee, Soma, Shih, Chiaho
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102108/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10982356/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.19.9099-9105.2000
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